High-Protein Supreme Pizza Casserole
A meat and cheese casserole with pepperoni and mushrooms — ready in 35 minutes
This high-protein supreme pizza casserole layers browned ground meat and a no-sugar sauce with cheese, pepperoni, mushrooms, and peppers, then bakes until the top is melted, like the dish. Each serving has 32 g of protein and 6 g net carbs.
Low carb, sugar-free, and no crust.
Why you’ll love this casserole
- 32g protein per serving
- 6g net carbs
- Pepperoni, mushrooms, and peppers
- Ready in about 35 minutes
- No crust
- One dish
Health notes
- Protein: Ground meat, cheese, and pepperoni.
- Low carb: No crust, and a no-sugar sauce.
- Sugar-free: Sauce with no added sugar.
- Keto-friendly: Each serving stays around 6g net carbs if the sauce is measured.
Key element — drain the meat
A wet meat layer makes the casserole greasy. Brown and drain it before it goes in the dish, so the top browns like the photo.
Ingredients
Casserole (6 servings)
- 1½ lb ground beef or turkey
- 1 tsp Italian seasoning
- ½ tsp garlic powder
- ½ tsp salt
- ¼ tsp black pepper
- 1 cup no-sugar pizza sauce or marinara
- 2 cups shredded mozzarella
- ½ cup grated Parmesan
- 3 oz pepperoni slices
- 1 cup sliced mushrooms
- ½ cup chopped green bell pepper
Swaps
- Turkey: Same weight. Fat drops a little.
- A crust or a sugar sauce: Not in the 6g number.
- No pepperoni: Protein drops a little.
- Extra pepper: Carbs rise a little.
Instructions
| 1 | Heat the oven. Heat to 400°F (200°C). Oil a 9×13-inch dish. |
| 2 | Meat. Brown the ground meat with Italian seasoning, garlic powder, salt, and pepper. Drain the fat. Stir in the sauce. |
| 3 | Layer. Spread the meat in the dish. Top with half the mozzarella, then mushrooms, peppers, and pepperoni. Finish with the rest of the mozzarella and the Parmesan, like the dish. |
| 4 | Bake. Bake 18–20 minutes until the cheese is melted and the edges bubble. Rest 5 minutes. This batch makes 6 servings. |
Pro tips
- Drain the meat. A wet layer greases the dish.
- A sugar-sweetened sauce is not in these numbers. Check the label.
- Rest 5 minutes so the slices hold.
- A crust turns this into a different recipe.
- Macros are per serving, 6 from this batch.
Nutrition
| Nutrient | Per serving |
|---|---|
| Calories | 420 |
| Protein | 32g |
| Net carbohydrates | 6g |
| Total carbohydrates | 7g |
| Fiber | 1g |
| Total fat | 28g |
| Sodium | 780mg |
Estimates based on ground meat, no-sugar sauce, mozzarella, Parmesan, pepperoni, mushrooms, and a measured pepper, divided into 6 servings. A crust and a sugar sauce are not included.
Variations
Turkey
Swap the beef for turkey. Fat drops a little.
No pepperoni
Skip it. Protein drops a little.
Extra mushrooms
Double them. Carbs stay close.
Spicy
A pinch of red pepper flakes on top.
Storage
| Method | Time | Notes |
|---|---|---|
| Refrigerator | Up to 4 days | Cover once cool |
| Reheat | 8 min | Covered, at 350°F, or a short microwave |
| Freezer | Up to 2 months | Portion before freezing |
FAQ
Test your knowledge
5 quick questions about this pizza casserole
1. Protein per serving?
2. Net carbs per serving?
3. What keeps the dish from going greasy?
4. About how long does this take?
5. What is not in the 6g number?
